BIOLOGICS FOR NASAL CONDITIONS
Dr Sandeep Uppal and his team at The ENT Clinic are at the forefront of employing advanced treatments for nasal conditions, including the use of biologics for nasal polyposis and nasal allergies. Biologics are a class of medications derived from living cells and are designed to target specific components of the immune system. They have gained prominence in recent years for their effectiveness in treating various chronic conditions, including severe asthma, rheumatoid arthritis, and certain skin conditions.
BIOLOGICS FOR NASAL POLYPOSIS
Biologics like Dupilumab are increasingly being used for treating severe cases of nasal polyposis that are unresponsive to traditional treatments such as corticosteroids. These medications are often considered for treating severe eosinophilic forms of chronic sinusitis with nasal polyps, especially when other treatments have proven ineffective. These medications work by inhibiting specific pathways involved in inflammation, thus reducing the size of the polyps and alleviating symptoms like nasal obstruction and loss of smell.
Dr Sandeep Uppal and his team are committed to a patient-centric approach, providing comprehensive information and closely monitoring patients who are on Anti-IL5 therapies. This ensures that the treatment is not only effective but also safe for the patient.
BIOLOGICS FOR NASAL ALLERGY
Similarly, biologics are also proving effective in managing severe nasal allergies that are unresponsive to antihistamines and other traditional medications. By targeting specific cytokines and inflammatory pathways, these drugs can offer significant relief from symptoms such as sneezing, itching, and nasal congestion. Dr Sandeep keeps abreast of the latest advancements in biologics for nasal allergies and is experienced in tailoring these treatments to individual patient needs.
EVIDENCE-BASED APPROACH
Dr Sandeep and his team strictly adhere to evidence-based guidelines for the use of biologics in treating nasal conditions. Their commitment to scientific rigor ensures that patients receive the most current and effective treatment available.
SAFETY AND MONITORING
The use of biologics is generally well-tolerated but requires close monitoring for potential side effects, such as increased susceptibility to infections. Dr Sandeep and his team place a high emphasis on patient safety and will conduct regular follow-up appointments to monitor treatment efficacy and any potential adverse effects. Dr Sandeep Uppal and his team at The ENT Clinic are vigilant about informing patients regarding the potential side effects and precautions associated with Anti-IL5 therapies like Mepolizumab, Reslizumab, and Benralizumab. Here is a detailed overview:
POTENTIAL SIDE EFFECTS
- Injection Site Reactions: Redness, swelling, or itching at the injection site is common.
- Respiratory Issues: Some patients may experience a worsening of asthma symptoms or bronchospasm.
- Headaches: A common side effect that usually resolves with time.
- Fatigue: Patients may feel unusually tired or lethargic.
- Muscle Pain: Some people report mild to moderate muscle soreness or cramps.
- Hypersensitivity Reactions: Including rash, itching, or severe allergic reactions.
- Elevated Blood Parameters: Changes in blood counts or liver enzymes may occur and are usually monitored via regular blood tests.
- Increased Risk of Infections: Particularly upper respiratory tract infections.
PRECAUTIONS TO BE TAKEN DURING TREATMENT
- Prior Allergy Assessment: A thorough review of any past allergic reactions to similar medications is essential.
- Concurrent Medications: A complete medication review is undertaken to identify potential drug interactions.
- Pregnancy and Breastfeeding: These therapies should be used cautiously in pregnant or breastfeeding women, and only if the benefits outweigh the risks.
- Vaccinations: It’s advisable to update vaccinations before starting therapy, as the medication could potentially interfere with the effectiveness of certain vaccines.
- Regular Monitoring: Blood tests to monitor eosinophil levels, liver function, and other parameters are often performed.
- Emergency Plan: Due to the risk of severe allergic reactions, an emergency action plan is usually discussed with the patient.
- Informed Consent: Detailed discussions are held with the patient to ensure they are fully aware of the risks and benefits of the treatment.
